Melinacidins, a new family of antibiotics.

نویسندگان

  • A D Argoudelis
  • F Reusser
چکیده

Melinacidin is a crystalline mixture of closely related antibacterial agents produced by Acrostalagmus cinnabarinus var. melinacidinus. Melinacidin inhibits a variety of Gram-positive bacteria in vitro but is found to be toxic and ineffective in the treatment of experimental bacterial infections in mice. Melinacidin which inhibits the growth of KB and L-1210 cells in tissue culture appears to belong to the "3,6-epidithiadiketopiperazine" group of antibiotics.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 24 6  شماره 

صفحات  -

تاریخ انتشار 1971